Recent Thesis Defense Presentations

isaac elizabeth

Student:  Elizabeth Isaac

Thesis Advisor:  Jan Grimm, MD, PhD

Date of Thesis Defense:  5/24/2024

TITLE:  "Harnessing the Therapeutic Potential of Iron and Reactive Oxygen Species (ROS) in the Treatment of Solid Tumors"


Winson Cai

Student:   Winson Cai

Thesis Advisor:  David Scheinberg, MD, PhD

Date of Thesis Defense:  5/13/2024

TITLE:  "Augmenting CAR T Cell Functions with LIGHT"


herrera

Student:  Pamela S. Hatfield (Herrera)

Thesis Advisor:  Marcel van den Brink, PhD

Date of Thesis Defense:  5/7/2024

TITLE:   "Microbiota-Derived Indoxyl Sulfate Enhances CAR T Cell Cytotoxicity in a Lymphoma Tumor Model"


ng brandon

Student:   Brandon Ng

Thesis Advisor:   Marcel Van den Brink, PhD

Date of Thesis Defense:  4/26/2024

TITLE:  "Engineered Il-18 Secretion and Multi-Antigen Targeting Enable  CAR T cells to Eliminate Multiple Myeloma with Low Antigen Expression in an Immunocompetent Mouse Model"


falci jessica

Student:   Jessica Falci

Thesis Advisor:   Yueming Li, PhD

Date of Thesis Defense:  4/25/2024

TITLE:   "Development and Mechanism of Autophagy Modulators for Treatment of Neurodegenerative Disorders"


Bai Yang

Student:   Yang Bai

Thesis Advisor:   Vivek Mittal, PhD

Date of Thesis Defense:  4/3/2024

TITLE:  "Epigenetic Regulation of Chromosomal Instability in Triple-Negative Breast Cancer"


Mildred Unti

Student: Mildred Unti

Thesis Advisor: Samie Jaffrey, MD, PhD

Date of Thesis Defense:  3/25/2024

TITLE:  "A Method for Expressing Circular mRNA in Mammalian Cells and its Use as A Therapeutic and Research Tool"


 

Kurtz Keifer

Student:  Keifer Kurtz

Thesis Advisor:  David Scheinberg, MD, PhD

Date of Thesis Defense:  1/17/2024

TITLE:  "Orthogonal Approaches for Enhancing Cellular Immunotherapies"


nease leona

Student:  Leona Nease

Thesis Advisor:  Elena Piskounova, PhD

Date of Thesis Defense:  12/6/2023

TITLE:   "Selenocysteine tRNA Methylation as an Antioxidant Mechanism in Melanoma Metastasis"


Kyeara Mack

Student:  Kyeara Mack

Thesis Advisor:  Jason Lewis, PhD

Date of Thesis Defense:  11/13/2023

TITLE:    "Antibody-Based Theranostics in Ovarian Cancer: Targeting MUC16 for Diagnosis and Radioimmunotherapy"


boby melissa

Student:  Melissa Boby

Thesis Advisor:  Derek Tan, PhD

Date of Thesis Defense:  11/8/2023

TITLE:   "Development of Adenylation Enzyme Inhibitors as Novel Antibiotics"


Krysta Dikun

Student:  Krysta DiKun

Thesis Advisor:  Lorraine Gudas, PhD

Date of Thesis Defense:  9/18/2023

TITLE:  "Investigating the Roles of Retinoic Acid Receptor (RAR) Alphaand Beta in Kidney Cell Types"


planck kyle

Student:  Kyle Planck

Thesis Advisor:  Kyu Rhee, PhD

Date of Thesis Defense:  8/17/2023

TITLE:  "Harnessing Chemical Biology and Metabolomics for Preclinical TB Drug Discovery"

 


dong lauren

Student:  Lauren Dong

Thesis Advisor:  Taha Merghoub, PhD

Date of Thesis Defense:  8/9/2023

TITLE:   "Intermittent MEK Inhibition with GITR Co-Stimulation Rescues T Cell Function and Sensitizes Solid Tumors to CTLA-4 Blockade"


Broderick Corless

Student:  Broderick Corless

Thesis Advisor:   Derek Tan, PhD

Date of Thesis Defense:  8/2/2023

TITLE:   "EpoxySEAKER: CAR T-Cell Model for Targeted Local Biosynthesis of Therapeutic Warheads"


khan jonathan

Student:  Jonathan Khan

Thesis Advisor:  Jedd Wolchok, PhD

Date of Thesis Defense:  7/6/2023

TITLE:   "Rational Development of an Optimized CAR T Cell Platform for Therapy of Glioblastoma"


silberman pedro

Student:  Pedro Silberman

Thesis Advisor:   David Scheinberg, MDPhD

Date of Thesis Defense:  7/5/2023

TITLE:   "Tumor Microenvironment Actuated T-Cells (MEAT-Cells) to Conditionally Express Chimeric Antigen Receptors and Mitigate Lethal Toxicity"


Jiayi Yuan

Student:  Jiayi "Cassie" Yuan

Thesis Advisor:  Lorenz Studer, PhD

Date of Thesis Defense:  6/29/2023

TITLE:  "Genome-Wide Loss-of-Function Screens in Human Microglia to Identify Novel HSV1 Susceptibility Factor"


jonas lauren

Student:   Lauren Jonas

Thesis Advisor:   Yueming Li, PhD

Date of Thesis Defense:  4/6/2023

TITLE:   "Interferon Inducible Transmembrane Protein 3 in Alzheimer’s Disease and Tauopathy"


tylawsky daniel

Student:   Daniel Tylawsky

Thesis Advisor:  Daniel Heller, PhD

Date of Thesis Defense:  4/5/2023

TITLE:   "Drug Delivery to Intracranial Tumors by Active Transport of Targeted Nanocarriers"


pharmacology graduate program new york city

Student:   Thomas Rossetti

Thesis Advisor:  Jochen Buck, MD, PhD & Lonny Levin, PhD

Date of Thesis Defense:  1/26/2023

TITLE:  "Optimizing Small Molecule Inhibitors of Soluble Adenylyl Cyclase (sAC) For Use as Male Contraceptives"


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